Cromwell's rule, named by statistician Dennis Lindley, states that the use of prior probabilities of 1 ("the event will definitely occur") or 0 ("the event will definitely not occur") should be avoided, except when applied to statements that are logically true or false, such as 2+2 equaling 4.

The reference is to Oliver Cromwell, who wrote to the General Assembly of the Church of Scotland on 3 August 1650, shortly before the Battle of Dunbar, including a phrase that has become well known and frequently quoted:

I beseech you, in the bowels of Christ, think it possible that you may be mistaken.

As Lindley puts it, assigning a probability should "leave a little probability for the moon being made of green cheese; it can be as small as 1 in a million, but have it there since otherwise an army of astronauts returning with samples of the said cheese will leave you unmoved." Similarly, in assessing the likelihood that tossing a coin will result in either a head or a tail facing upwards, there is a possibility, albeit remote, that the coin will land on its edge and remain in that position.

If the prior probability assigned to a hypothesis is 0 or 1, then, by Bayes' theorem, the posterior probability (probability of the hypothesis, given the evidence) is forced to be 0 or 1 as well; no evidence, no matter how strong, could have any influence.

A strengthened version of Cromwell's rule, applying also to statements of arithmetic and logic, alters the first rule of probability, or the convexity rule, 0 ≤ Pr(A) ≤ 1, to 0 < Pr(A) < 1.